Saturday, May 18, 2024

Inexpensive drug arginine could enhance effectiveness of radiation therapy, study indicates

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute. The study, published Nov. 5 in Science Advances, reported the results of administering arginine, which can be delivered in oral form, prior to standard radiation therapy in 31 patients who had brain metastases. Nearly 78% had a complete or partial response in their brain tumours over the follow-up period of up to four years, while only 22 percent of the 32 patients who received a placebo prior to radiotherapy had such a response. The promising results have prompted the team to start to plan further studies of arginine on its own or in combination with other anticancer treatments. 

 

https://medicalxpress.com/news/2021-11-arginine-inexpensive-oral-drug-therapy.html

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